Mouse Anti-NME2/nm23-H2/NDPK-B Antibody MBS4380647 from MyBioSource.com

Product Specs
ItemMouse Anti-NME2/nm23-H2/NDPK-B Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS4380647
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ApplicationsImmunohistology (Formalin-Fixed)
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
ReactivityHuman. Others not tested
TargetNME2/nm23-H2/NDPK-B
IsotypeIgG2a
Molecular Weight17kDa
CloneCPTC-NME2-2
HostMouse
ImmunogenThe nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor
NCBI Full Gene NameNME1-NME2 readthrough, NME/NM23 nucleoside diphosphate kinase 2
NCBI Gene AliasesNM23-LV, NDKB, NMELV, NDPKB, NM23-H2, NDPK-B, NM23B, PUF
ClonalityMonoclonal